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IBB POSTECH

Faculty

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Lab : Molecular Biology, Virology & Immunology
Office : + 82-54-279-2294 / Lab :+ 82-54-279-0888
Homepage : -
E-Mail :

Profile

Professor

Department of Life Science 

Division of Molecular and Life Sciences 

Molecular Biology, Virology & Immunology

 

 

1987
1987-1988
1988-1989

Ph.D., University of Minnesota
University of Minnesota, Post-doc
Harvard Medical School, Post-doc


Research Interests

Viral Immunology
Our laboratory is focusing on understanding the immunological mechanisms in inducing effective immune responses against viral infections. Also, we are interested in pathogenic mechanisms underlying viral persistence and HCV oncogenesis. The target viruses of interest are human immunodeficiency virus type1 (HIV-1), an etiological agent of AIDS, and hepatitis C virus (HCV) causing chronic hepatitis and hepatoma.

Selected Publications

1.Therapeutic effect of DNA vaccines combined with chemotherapy in a latent infection model after aerosol infection of mice with Mycobacterium tuberculosis. Sang-Jun Ha, Bo-Young Jeon, Seung-Chul Kim, Doo-Jin Kim, Man-Ki Song, Young-Chul Sung, and Sang-Nae Cho, Gene therapy. 2003 Sep; 10(18): 1592-9

2.IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in HCV E2 DNA immunization. Sang-Jun Ha, Kwan-Hyuck Baek, Doo-Jin Kim, Young-Dae Yun and Young Chul Sung, (2004) J. of Immunology 2004 Jan 1; 172(1): 525-531

3.IL-12 priming during in vitro antiegenic stimulation changes properties of CD8 T cells and increases generation of effector and memory cells. Jun Chang, Jae Ho Cho, Seung Woo Lee, So Young Choi, Sang Jun Ha and Young Chul Sung, J. of Immunology. 2004, Mar 1; 172(5)2818-2826

4.Protective effect of DNA vaccine during chemotherapy on reactivation and reinfection of Mycobacterium tuberculosis. Dr. Sang Jun Ha , Dr. Bo Young Jeon , Mr. Je-In Youn , Dr. Seung Chul Kim , Prof. Sang Nae Cho, and Young Chul Sung. Gene therapy. 2005 Apr: 12(7): 634-8

5.Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor, Jin Hyun-Tak, Youn Je-In, Kim Hye-Ju, Lee Jee-Boung, Ha Sang-Jun, Koh Jong, Sung Young-Chul, Human Gene Therapy 2005 Mar; 16(3);328-38