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RESEARCH OVERVIEW
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Membrane signaling station (MSS) is a new concept for a functional unit for cellular communication with the environment, which is a specific membrane region or a big complex comprising various receptors and signaling proteins, not just individual receptor proteins as in the traditional concept. In the neurobiology or immunology fields, a concept similar to MSS has already been introduced. For example, a "synapse” is a result of communications among the neighboring cells.

We have studied Membrane signaling station (MSS) at the meso level which is not often explored despite its importance and potential for various applications to medicine, drug development, plant biomass production, and bio-mechanical engineering.

Membrane meso machinery and in vivo dynamics have been studied using platform technologies developed and the resulted technologies, concepts and models are applied to the research of bio-defense system, plant biomass production, and biomechanical engineering.

Research has been performed in 5 specific subjects;
1) Development of platform technology,
2) Meso architectural membrane signaling station,
3) Biodefense system and its application,
4) Plant biomass production, and
5) Cell surface engineering.

LSS : Ligand signaling station
SMSS : Signaling mediator secretory station
PIMS : pathogen infection mediation station
FLSS : flowering and light signaling station
PTSS : Protein targeting mediation station
OCT : Optical coherence tomography
HsMf-TP-MICROSCOPE : HsMf two photon microscope
EPR : electron paramagnetic resonance
Sp-FRET : single particle fluorescence resonance energy transfer