Youngsook Lee, Ph.D.

Professor
Department of Life Science
Division of Molecular and Life Sciences
Plant Cell Biology

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Publications Abstract
E-mail ylee@postech.ac.kr
Office : + 82-54-279-2296 / Lab :+ 82-54-279-5980
Laboratory Lab. of the Plant Cell Biology

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Profile |  Research Interests  |  Selected Publications

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Profile

1988
1988-1990

Ph.D., University of Connecticut,  Storrs, CT, USA
Postdoctoral Fellow, Harvard University

 

 

     

Research Interests

Plant Cell Biology Laboratory
We have two aims of research. First is to understand the mechanisms of transport and detoxification of the pollutants such as heavy metals and herbicides by plants. The knowledge obtained from this project can be used for development of plants that can be useful for phytoremediation or safe crops that do not absorb pollutants.  Second is to understand how plant cells sense and respond to various internal and external changes such as light, water stress, pollutants and herbivores. We identify the components of the signal transduction pathways that lead to stomatal movements and plant defense responses, and investigate how they interact.  The knowledge obtained from this project can be used for development of plants that are tolerant to drought, pathogen, and other stresses, or those that can respond rapidly and efficiently to physiological signals to open or close stomata, thus optimizing photosynthesis and water use efficiency.     
We use molecular biological techniques, immunolocalization, as well as electrophysiological techniques.  For example, patch clamping technique is powerful in providing information on the activities of individual ion transporters. We also use expression systems such as Xenopus oocytes to identify the functionss of plant transporter genes.  

      

Selected Publications 

  1. J. Park, Y. Gu, Y. Lee, Z. Yang, Y. Lee (2004) Phosphatidic acid induces leaf cell death in Arabidopsis by activating the ROP GTPase-mediated pathway of reactive oxygen species generation. Plant Physiology, 134: 129-136
  2. J. Jeong, S. Suh, C.. Guan, Y.-F. Tsay, N. Moran, C. J Oh, C. S. An, K. Demchenko, K. Pawlowski, and Y. Lee (2004) A nodule-specific dicarboxylate transporter from Alnus glutinosa is a member of the PTR family.  Plant Physiology 134: 969-978
  3. W.-Y. Song, E. Martinoia, J. Lee, D. Shim, D.-Y. Kim, E. Vogt, K.S. Choi, I. Hwang and Y. Lee (2004) A novel family of cysteine-rich membrane proteins mediates cadmium resistance in Arabidopsis.  Plant Physiology 135: 1027-1039
  4. J. Lee, D. Shim, W.-Y. Song, I. Hwang, and Y. Lee (2004) Arabidopsis metallothioneins 2a and 3 enhance resistance to cadmium when expressed in Vicia faba guard cells. Plant Molecular Biology 54: 805-815  
  5. M. Lee, K. Lee, J. Lee, E. W. Noh, and Y. Lee (2005) AtPDR12 Contributes to Lead Resistance in Arabidopsis. Plant Physiology 138:827-36
  6. E.-J. Koh, W.-Y. Song, Y. Lee, K.H. Kim, K. Kim, N. Chung, K. Lee, S.-W.-Hong, H. Lee (2006) Expression of yeast cadmium factor 1 (YCF1) confers salt tolerance to Arabidopsis thaliana.  Plant Science170: 534-541
  7. D.-Y. Kim, L. Bovet, S. Kushnir, E. W. Noh, E. Martinoia, Y. Lee (2006) AtATM3 is involved in heavy metal resistance in Arabidopsis. Plant Physiology: 140, 933-945
  8. D.-Y. Kim, L. Bovet, M. Maeshima, E. Martinoia, Y. Lee (2007) The ABC transporter AtPDR8 is a cadmium pump conferring heavy metal resistance. Plant Journal: 50, 207-218

 

 

 

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